Dra. Ana Belén Cuenca González


Dra. Ana Belén Cuenca 
Organic and Pharmaceutical Chemistry
IQS School of Engineering
Universitat Ramon Llull
Vía Augusta 390, E-08017 Barcelona, Spain
Tel.:+34 932 672 413
Fax: +34 939 056 266
 
email: 
anabelen.cuenca@iqs.url.edu

Degree in Pharmacy (U. Valencia 1996); PhD in Pharmacy (Organic Chemistry, U. Valencia, 2001); Post-doctoral stay in “Institut de Recherche de Chimie Organique Fine (IRCOF), CNRS” (Rouen, France, 2002-04); Post-doctoral fellow in “Massachusetts Institute of Technology (MIT)” (USA, Prof. Stephen L. Buchwald, 2004-06); Juan de la Cierva/Consolider (U. Valencia, 2006-13); Assistant Professor (U. Valencia, 2011-13); Senior researcher in(URV, 2013-2016); Invited researcher in (U. Tokyo, Japan, Prof. M. Fujita, 2015)

Assistant Professor Sept. 2016-

 

SUBJECTS

Structural determination (GF); Biological Organic Chemistry (GB); Lab. Pharmaceutical Chemistry (GF)

 

RESEARCH LINES

  • Organo-mediated (as well as transition-metal) catalytic methodologies applied to create new C-X (X =, C, N, O, Si, B, H…) bond formation processes.
  • Application to the synthesis of biologically interesting compounds.

 

REPRESENTATIVE PUBLICATIONS

1.            Cuenca, Ana B.; Shishido, R.; Ito, H.; Fernández, E.“Transition-metal-free B–B and B–interelement reactions with organic molecules” Chem. Soc. Rev. 2017, 46, 415 – 430.

2.            La Cascia, E.; Cuenca, Ana B.*; Fernández, E.* “Opportune gem-Silylborylation of Carbonyl Compounds: A Modular and Stereocontrolled Entry to Tetrasubstituted Olefins” Chem. A Eur. J. 2016, 22, 18737-18741.

3.            Civit, M. G.; Royes, J.; Vogels, C.; Wescott, S.; Cuenca, A. B.*; Fernández, E.* “Strategic Trimethylsilyldiazomethane Insertion into pinB–SR Followed by Selective Alkylations” Org. Lett. 2016, 18, 3830-3833.

4.            Z. Majzik, A. B. Cuenca, N. Pavlicek, N. Miralles, G.Meyer, L. Gross, E. Fernández, “Synthesis of a naphthodiazaborole and its verification by planarization with AFM” ACS Nano, 2016, 10, 5340-5345.

5.            Cuenca, A. B.; Duplan, V.; Zigon, N.; Hoshio, M.; Fujita, M.; Fernández, E. “Undeniable Confirmation of the syn-Addition Mechanism for Metal-Free Diboration using the Crystalline Sponge Method” Chem. A Eur. J. 2016, 22, 4723-4726.

6.            Cuenca, A. B.*; Cid, J.; García-López, D.; Carbó, J. J.; Fernández, E. “Unsymmetrical 1,1-diborated multisubstituted sp3-carbons formed via a metal-free concerted-asynchronous mechanism” Org. Biomol. Chem. 2015, 13, 37, 9659-9664.

7.            Miralles, N.; Cid, J.; Cuenca, A. B.; Carbó, J.J.; Fernández, E. “Mixed diboration of alkenes in a metal-free context” Chem. Comm. 2015, 51, 1693-1696.

8.            Gimeno, A.; Rodríguez-Gimeno, A.; Cuenca, A. B.; De Arellano, C. R.; Medio-Simón, M.; Asensio, G. “Gold(I)-catalysed cascade reactions in the synthesis of 2,3-fused indole derivatives” Chem Comm. 2015, 51, 12384-12387.

9.            Gimeno, A. M.; Cuenca, A. B.; Suárez-Pantiga, S.; Medio-Simón, M.; De Arellano, C. R.; Asensio, G. “Competitive Gold Activation Modes in Terminal Alkynes: An Experimental Mechanistic Study” Chem. A Eur. J. 2014, 20, 683-688.

10.          Cuenca, A. B.; Montserrat, S.; Hossain, K. M.; Mancha, G.; Lledós, A.; Medio-Simón, M.; Ujaque, G.; Asensio, G. "Gold(I)-Catalyzed Intermolecular Oxyarylation of Alkynes: Unexpected Regiochemistry in the Alkylation of Arenes" Org. Lett. 2009, 11, 4906-4909.

11.          Martín, R.; Larsen, C. H.; Cuenca, A.; Buchwald, S. L. “Cu-Catalyzed Tandem C-N Bond Formation for the Synthesis of Pyrroles and Heteroarylpyrroles” Org. Lett. 2007, 9, 3379-3382.

12.          Martín, R.; Cuenca, A.; Buchwald, S. L. "Sequential Copper-Catalyzed Vinylation/Cyclization: An Efficient Synthesis of Functionalized Oxazoles" Org. Lett. 2007, 9, 5521-5524.

13.          Cuenca, A. B.; Mancha, G.; Asensio, G.; Medio-Simón, M. "Water compatible gold(III)-catalyzed synthesis of unsymmetrical ethers from alcohols" Chem. Eur. J. 2008, 14, 1518-1523.