Subjects

Molecular Biology of the Cell, Cell Cultures and Tissue Engineering, Integrated Laboratory (Masters of Bioengineering)

Research Lines

• Design and synthesis of nanometric biomaterials analog to extracellular matrices
• Development of instructive tri-dimensional environments for functional differentiation of stem cells
• Environmental reprogramming of adult cells to develop regenerative medicine platforms

Representative Publications

Genové E, Schmitmeier S, Sala A, Borrós S, Favia P, Lopez L, di Bartolo L, Bader A, Griffith L & Semino CE. (2009). A synthetic functionalized self-assembling peptide hydrogel enhance maintenance of hepatocyte activity in vitro. Journal of Cellular and Molecular Medicine (In press).

Marí-Buyé N, Fernández Muiños T, Semino, CE (2009). Methods In Bioengineering (MIB). 3D-Tissue Engineering. Series Editors Martin L. Yarmush, Helen Andrus, & Robert S. Langer). ARTECH HOUSE (Boston/London).

Quintana L, Fernández Muiños T, Genové E, del Mar Olmos M, Borrós S, & Semino CE. (2009) Early tissue patterning is recreated by mouse embryonic fibroblasts in a three-dimensional environment. Tissue Engineering Part A 15(1): 45-54.

Hernández Vera R, Genové E, Alvarez L, Borrós S, Kamm R, Lauffenburger D & Semino CE. (2009) Interstitial fluid flow intensity modulates endothelial sprouting in restricted Src activated cell clusters during capillary morhogenesis. Tissue Engineering Part A 15 (1): 175-185.

Quintana L, zur Nieden NI, Semino CE. (2009). Morphogenetic and regulatory mechanisms during developmental chondrogenesis. Tissue Engineering Part B 15 (1): 29-41.

Research Groups