• Dr. Jordi Teixidó Closa

Dr. Jordi Teixidó i Closa
Grup de Química Farmacèutica
IQS School of Engineering
Universitat Ramon Llull
Via Augusta 390, E-08017
Barcelona, Spain
Tel.:+34 932 672 000
Fax: +34 939 056 266

email: 
jordi.teixido@iqs.url.edu

Doctor Enginyer Químic (1991, IQS). Llicenciat en Ciències Químiques (1993, URL). Enginyer Químic (1987, IQS)
Research Fellow, Rohm & Haas Agrochem. Div, USA (1998)

Professor Catedràtic, 2005-
Responsable del Laboratori de Disseny Molecular
Secretari General 2012 - 2014
Degà d'IQS School of Engineering 2014 - 2020
Vicerector d'Ordenació i Qualitat Acadèmica de la URL 2020 - 

 

Assignatures

Determinació Estructural, Disseny Molecular, Química Farmacèutica

 

Línies de Recerca

  • Disseny Molecular: Química Computacional i mètodes Quimiomètrics aplicats al disseny i síntesis de noves molècules.
  • Disseny i síntesi de nous inhibidors de GPCR,  TK i RTK (càncer), VIH (Sida) i VHC (Hepatitis C).

 

Publicacions rellevants

Oliveras, J.M.; Puig de la Bellacasa, R.; Estrada-Tejedor, R.; Teixidó, J.; Borrell, J.I., 1,6-Naphthyridin-2(1H)-ones: Synthesis and Biomedical Applications, Pharmaceuticals 2021,14, 1029. https://doi.org/10.3390/ph14101029

Iñaki Galve; Raül Ondoño; Claudi de Rocafiguera; Raimon Puig de la Bellacasa; Xavier Batllori; Cristina Puigjaner; Mercè Font-Bardia; Oriol Vallcorba; Jordi Teixidó and José I. Borrell, A captured room temperature stable Wheland intermediate as a key structure for the orthogonal decoration of 4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones, Organic & Biomolecular Chemistry, 2020, Vol. 18, Num. 48, 9810-9815.

Bou-Petit, Elisabeth; Plans, Arnau; Rodríguez-Picazo, Nieves; Torres-Coll, Antoni; Puigjaner, Cristina; Font-Bardia, Mercè; Teixidó, Jordi; Ramon y Cajal, Santiago; Estrada-Tejedor, Roger; Borrell, José I., C4-C5 fused pyrazol-3-amines: When the degree of unsaturation and electronic characteristics of the fused ring controls regioselectivity in Ullmann and acylation reactions, Organic & Biomolecular Chemistry, 2020, Vol. 18, Num. 27, 5145-5156.

Guillem Jubete; Raimon Puig de la Bellacasa; Roger Estrada-Tejedor; Jordi Teixidó; José I. Borrell, Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications, Molecules, 2019, Vol. 24, Num. 22, 4161.

Recasens-Zorzo, Clara; Cardesa-Salzmann, Teresa; Petazzi, Paolo; Ros-Blanco, Laia; Esteve-Arenys, Anna; Clot, Guillem; Guerrero-Hernandez, Martina; Rodriguez, Vanina; Soldini, Davide; Valera, Alexandra; Moros, Alexandra; Climent, Fina; Gonzalez-Barca, Eva; Mercadal, Santiago; Arenillas, Leonor; Calvo, Xavier; Mate, Jose Luis; Gutierrez-Garcia, Gonzalo; Casanova, Isolda; Mangues, Ramon; Sanjuan-Pla, Alejandra; Bueno, Clara; Menendez, Pablo; Martinez, Antonio; Colomer, Dolors; Estrada-Tejedor, Roger; Teixido, Jordi; Campo, Elias; Lopez-Guillermo, Armando; Borrell, Jose Ignacio; Colomo, Luis; Perez-Galan, Patricia; Roue, Gael, Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma, Haematologica, 2018, Vol. 103, Num. 9, 778-788.

Àlex L. González , Piotr Konieczny , Beatriz Llamusi, Estefanía Delgado-Pinar, José I. Borrell, Jordi Teixidó, Enrique García-España, Manuel Pérez-Alonso, Roger Estrada-Tejedor , Rubén Artero, In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models, PLoS One, 2017, https://doi.org/10.1371/journal.pone.0178931.

P. Balsas, A. Esteve-Arenys, J. Roldán, L. Jiménez, V. Rodríguez, J. G. Valero, A. Chamorro-Jorganes, R. Puig de la Bellacasa, J. Teixidó, A. Matas-Céspedes, A. Moros, A. Martínez, E. Campo, A. Sáez-Borderías, J. I. Borrell, P. Pérez-Galán, D. Colomer and G. Roué, Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma, Journal Of Hematology & Oncology, 2017, Vol. 10, Num. 1, 80.

Àlex L. González; Jordi Teixidó; José I. Borrell; Roger Estrada-Tejedor, On the applicability of Elastic Network Models for the study of RNA CUG trinucleotide repeat overexpansion. PLoS One, 2016, http://dx.doi.org/10.1371/journal.pone.0152049

Marta Camarasa, Raimon Puig de la Bellacasa, Alex L. Gonzalez, Raül Ondoño, Roger Estrada, Sandra Franco, Roger Badia, Jose Esté, Miguel Angel Martínez, Jordi Teixidó, Bonaventura Clotet, José I. Borrell, Design, synthesis and biological evaluation of pyrido[2,3-d]pyrimidin-7-(8H)-ones as HCV inhibidors. European Journal of Medicinal  Chemistry, 2016, 115, 463-483.

Puig de la Bellacasa, Raimon; Gibert, Albert; Planesas, Jesus M.; Ros-Blanco, Laia; Batllori, Xavier; Badia, Roger; Clotet, Bonaventura; Este, Jose; Teixido, Jordi; Borrell, Jose  I., Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors, Organic & Biomolecular  Chemistry, 2016, 14, #4, 1455-1472.         

 

Grups d'investigació

Grup de Química Farmacèutica