• Dr. Pablo Leivar Rico

Dr. Pablo Leivar 
Laboratori de Bioquímica
Unitat de Biologia Sintètica i Biotecnologia de Microalgues
Grup de Química Biològica y Biotecnologia (GQBB)
Departament de Bioenginyeria
IQS School of Engineering
Universitat Ramon Llull
Via Augusta 390, E-08017 Barcelona, Spain
Tel. +34 93 267 20 00
Fax +34 93 205 62 66

email: 
pablo.leivar@iqs.url.edu

Llicenciat en Bioquímica (Universitat de Barcelona, 1998)
Doctor en Bioquímica (Universitat de Barcelona, 2003)

Investigador postdoctoral (University of California-Berkeley, 2004-2009)
Investigador júnior (Centre for Research in Agricultural Genomics, 2010-2014)
Professor Contractat Doctor (IQS, 2014 - 2020)
Professor Titular (IQS, 2020 -)
Coordinador del Grau en Biotecnologia (IQS, 2017 -)

Més informació: https://planaslab.iqs.edu/people/pablo-leivar/

 

AssignaturES

Tecnologia d’ADN recombinant (Grau en Biotecnologia)
Genòmica, Proteòmica, Metabolòmica (Grau en Biotecnologia)
Biotecnologia Vegetal (Grau en Biotecnologia)
Seminaris Interdisciplinars (Grau en Biotecnologia)

Laboratori d’Enginyeria Genètica i Metabòlica (Màster en Bioenginyeria)
Laboratori Fonamental, complements formatius (Màster en Bioenginyeria)
Enginyeria genètica i de proteïnes, complements formatius (Màster en Bioenginyeria)

 

LINIES DE RECERCA

Biologia Sintètica i Biotecnologia Molecular de Microalgues Fotosintètiques:
  • Enginyeria genètica i metabòlica de microalgues per a la producció sostenible de bioproductes d’alt valor
  • Enginyeria del metabolisme de glicolípids al cloroplast de la microalga verda Chlamydomonas reinhardtii
  • Control optogenètic de l'expressió gènica com a eina de biologia sintètica
  • Sistemes fotosensors en plantes basats en els fotoreceptors fitocrom (phy) i els factors de transcripció que interaccionen amb el phy (PIFs)
Més informació: https://planaslab.iqs.edu/research/synthetic-biology-and-molecular-biotechnology-in-green-microalgae/

 

PublicacionS RELLEVANTS

ResearcherID: D-7808-2017
ORCID: 0000-0003-4878-3684

Llistat complert: https://scholar.google.es/citations?user=m5b_glAAAAAJ&hl=es

Rovira A, Sentandreu M, Nagatani A, Leivar P, Monte E. (2021). The Sequential Action of MIDA9/PP2C.D1, PP2C.D2, and PP2C.D5 Is Necessary to Form and Maintain the Hook After Germination in the Dark. Front Plant Sci 12, 636098.

Chi J, Cova M, de Las Rivas M, Medina A, Borges RJ, Leivar P, Planas A, Usón I, Hurtado-Guerrero R, Izquierdo L. (2020). Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development. mBio 11:e02045-20.

Leivar P, Martín G, Soy J, Dalton-Roesler J, Quail PH, Monte E. (2020). Phytochrome-imposed inhibition of PIF7 activity shapes photoperiodic growth in Arabidopsis together with PIF1, 3, 4 and 5.  Physiol Plant 169, 452-466.

Zhang Y, Pfeiffer A, Tepperman JM, Dalton-Roesler J, Leivar P, Gonzalez Grandio E, Quail PH. (2020). Central clock components modulate plant shade avoidance by directly repressing transcriptional activation activity of PIF proteins. Proc Natl Acad Sci U S A 117, 3261-3269.

Martín G, Rovira A, Veciana N, Soy J, Toledo-Ortiz G, Gommers CMM, Boix M, Henriques R, Minguet EG, Alabadí D, Halliday KJ, Leivar P, Monte E. (2018). Circadian Waves of Transcriptional Repression Shape PIF-Regulated Photoperiod-Responsive Growth in Arabidopsis. Current Biology 28, 311-318.

Martín G, Leivar P, Ludevid D, Tepperman JM, Quail PH, Monte E. (2016). Phytochrome and retrograde signalling pathways converge to antagonistically regulate a light-induced transcriptional network. Nature Communications 7, 11431.

Soy J, Leivar P, González-Schain N, Martín G, Diaz C, Sentandreu M, Al-Sady B, Quail PH, Monte E. (2016). Molecular convergence of clock and photosensory pathways through PIF3-TOC1 interaction and co-occupancy of target promoters. Proc Natl Acad Sci USA 113, 4870-5.

Leivar P, and Monte E (2014). PIFs: Systems Integrators in Plant Development. Plant Cell 26, 56-78.

Leivar P, Tepperman JM, Cohn MM, Monte E, Al-Sady B, Erickson E, and Quail PH (2012). Dynamic antagonism between phytochromes and PIF family basic helix-loop-helix factors induces selective reciprocal responses to light and shade in a rapidly responsive transcriptional network in Arabidopsis. Plant Cell 24, 1398-1419.

Leivar P, and Quail PH (2011). PIFs: pivotal components in a cellular signaling hub. Trends in Plant Science 16, 19-28.

Leivar P, Antolin-Llovera M, Ferrero S, Closa M, Arro M, Ferrer A, Boronat A, and Campos N (2011). Multilevel control of Arabidopsis 3-hydroxy-3-methylglutaryl coenzyme A reductase by protein phosphatase 2A. Plant Cell 23, 1494-1511.

Leivar P, Tepperman JM, Monte E, Calderon RH, Liu TL, and Quail PH (2009). Definition of early transcriptional circuitry involved in light-induced reversal of PIF-imposed repression of photomorphogenesis in young Arabidopsis seedlings. Plant Cell 21, 3535-3553.

Leivar P, Monte E, Oka Y, Liu T, Carle C, Castillon A, Huq E, and Quail PH (2008). Multiple phytochrome-interacting bHLH transcription factors repress premature seedling photomorphogenesis in darkness. Current Biology 18, 1815-1823.

Leivar P, Monte E, Al-Sady B, Carle C, Storer A, Alonso JM, Ecker JR, and Quail PH (2008). The Arabidopsis phytochrome-interacting factor PIF7, together with PIF3 and PIF4, regulates responses to prolonged red light by modulating phyB levels. Plant Cell 20, 337-352..

  

GRUPS D'INVESTIGACIÓ

Grup de Química Biològica y Biotecnologia (GQBB)

Més informació: https://planaslab.iqs.edu/