• Dra. Cristina Fornaguera i Puigvert

Dr. Cristina Fornaguera i Puigvert
Grup d’Enginyeria de Materials (Gemat)
IQS School of Engineering
Universitat Ramon Llull
Via Augusta 390, E-08017
Barcelona, Spain
Tel.:+34 932 672 000
Fax: +34 939 056 266

email: 
cristina.fornaguera@iqs.url.edu

Doctora Recerca, Desenvolupament i Control de Medicaments (2015, Universitat de Barcelona).

Màster en Medicina Respiratòria (2012, Universitat Pompeu Fabra i Universitat de Barcelona).

Llicenciada en Biotecnologia (2010, Universitat Autònoma de Barcelona).

Investigadora Postdoctoral a Sagetis-Biotech SL (2015 – 2018).

Professora Contractada Doctora (IQS, 2018 ---).

 

Professora de Tecnologies Biomèdiques i Biomaterials (Grau en Biotecnologia); d’Immunologia (Grau en Biotecnologia); de Sistemes Avançats d’Alliberament de Fàrmacs (Grau en Farmàcia); de Laboratori Integrat (Grau en Biotecnologia) i de Laboratori de Biologia Molecular (Grau en Biotecnologia).

 

  • Nanosistemes polimèrics per aplicacions en biomedicina.
  • Disseny de sistems avançats d’alliberament de fàrmacs.
  • Disseny de vectors no-virals de teràpia génica.
  • Optimització de nanoformulacions amb vectorització a òrgans específics.

 

Fornaguera C., Grijalvo S., Galán M., Fuentes-Paniagua E., de la Mata F.J., Gómez R., Eritja R., Calderó G., Solans C., NOVEL NON-VIRAL GENE DELIVERY SYSTEMS COMPOSED OF CARBOSILANE DENDRON FUNCTIONALIZED NANOPARTICLES PREPARED FROM NANO-EMULSIONS AS NON-VIRAL CARRIERS FOR ANTISENSE OLIGONUCLEOTIDES. International Journal of Pharmaceutics 478(1) (2015) 113–123. DOI: 10.1016/j.ijpharm.2014.11.031

Fornaguera C.,Llinàs M., Solans C., Calderó G., DESIGN AND IN VITRO EVALUATION OF BIOCOMPATIBLE DEXAMETHASONE-LOADED NANOPARTICLE DISPERSIONS, OBTAINED FROM NANO-EMULSIONS, FOR INHALATORY THERAPY. Colloids and Surfaces B, 125(1) (2015), 58–64. DOI: 10.1016/j.colsurfb.2014.11.006

Fornaguera C., Calderó G., Mitjans M., Vinardell P., Solans C., Vauthier C., INTERACTION OF PLGA NANOPARTICLES WITH BLOOD COMPONENTS: PROTEIN ADSORPTION, COAGULATION, ACTIVATION OF THE COMPLEMENT SYSTEM AND HEMOLYSIS STUDIES. Nanoscale, 7 (2015), 6045–6058. DOI: 10.1039/C5NR00733J

Fornaguera C., Solans C., DESIGN OF MULTIFUNCTIONAL POLYMERIC NANOPARTICLES AS NANOCARRIERS FOR PHARMACEUTICAL APPLICATIONS. Proceedings of the “45th Jornadas Anuales CED”. 2015.

Fornaguera C., Calderó G., Solans C., Vauthier C., PROTEIN–NANOPARTICLE INTERACTIONS EVALUATION BY IMMUNOMETHODS: SURFACTANTS CAN DISTURB QUANTITATIVE DETERMINATIONS. European Journal of Pharmaceutics and Biopharmaceutics, 94 (2015), 284 – 290. DOI: 10.1016/j.ejpb.2015.05.025.

Fornaguera C.,Dols-Pérez A., Calderó G., García-Celma M.J., Camarasa J., Solans C., PLGA NANOPARTICLES PREPARED BY NANO-EMULSION TEMPLATING USING LOW-ENERGY METHODS AS EFFICIENT NANOCARRIERS THROUGH THE BLOOD-BRAIN BARRIER. Journal of Controlled release,211 (2015), 134 – 143. DOI: 10.1016/j.jconrel.2015.06.002.

Fornaguera C.,Feiner-Gracia N., Calderó G., Garcia-Celma M.J., Solans C., GALANTAMINE-LOADED PLGA NANOPARTICLES, FROM NANO-EMULSION TEMPLATING, AS NOVEL ADVANCED DRUG DELIVERY SYSTEMS TO TREAT NEURODEGENERATIVE DISEASES. Nanoscale, 7 (2015), 12076 – 12084. DOI: 10.1039/C5NR03474D

Fornaguera C.,Calderó G., Solans C., ELECTROLYTES AS A TUNING PARAMETER TO CONTROL NANOEMULSION AND NANOPARTICLE SIZE. RSC Advanced, 6 (2016), 58203 – 58211. DOI: 10.1039/c6ra09123g.

Fornaguera C.,Feiner-Gracia N., Calderó G., García-Celma M.J., Solans C., PLGA NANOPARTICLES AS IMAGING AGENTS: VERSATILE NANOSYSTEMS LOADED WITH FLUORESCENT DYES.  Colloids and Surfaces B, 147 (2016)201–209. DOI: 10.1016/j.colsurfb.2016.08.001.

Galán M., Fornaguera C., Ortega P., Calderó G., Lorente R., Jimenez J. L., de la Mata J., Muñoz-Fernandez M. A., Solans C., Gómez R., DENDRONIZED PLGA NANOPARTICLES WITH ANIONIC CARBOSILANE DENDRONS AS ANTIVIRAL AGENTS AGAINST HIV INFECTION. RSC Advances, 6 (2016) 73817-73826. DOI: 10.1039/C6RA13461K.

Fornaguera C.,Solans C., POLYMERIC NANOPARTICLES FOR DRUG DELIVERY IN NEUROLOGICAL DISEASES. Current Pathobiology Reports, 4(5) (2016) 1-9. DOI: 10.1007/s40139-016-0118-2

Fornaguera C.,Solans C., METHODS FOR THE IN VITRO CHARACTERIZATION OF NANOMEDICINES – BIOLOGICAL COMPONENTS INTERACTION. Journal of Personalized Medicine, 7(1), (2017) 1-16. DOI: 10.3390/jpm7010002

Fornaguera C.,Feiner-Gracia N., Dols-Perez A., Garcia-Celma M.J., Solans C., VERSATILE METHODOLOGY TO ENCAPSULATE GOLD NANOPARTICLES IN PLGA NANOPARTICLES OBTAINED BY NANO-EMULSION TEMPLATING. Pharmaceutical Research, 34(2), (2017) 1093 – 1103. DOI: 10.1007/s11095-017-2119-1

Fornaguera C.,Lázaro MA., Morera I., Cascante A., Guerra M., Rubió N., Blanco J., Borrós S., NOVEL PEPTIDE-DECORATED PACLITAXEL-LOADED POLYESTER-BASED NANOPARTICLES AS DELIVERY SYSTEMS FOR BRAIN TUMORS THERAPY.Frontiers in Bioengineering and Biotechnology (2016). Conference Abstract: 10th World Biomaterials Congress. DOI: 10.3389/conf.FBIOE.2016.01.00579

Calderó G., Fornaguera C., Zadoina L., Dols-Perez A., Solans C., DESIGN OF PARENTERAL MNP-LOADED PLGA NANOPARTICLES BY A LOW-ENERGY EMULSIFICATION APPROACH AS THERAGNOSTIC PLATFORMS FOR INTRAVENOUS OR INTRATUMORAL ADMINISTRATION. Colloids and Surfaces B: Biointerfaces 160, (2017) 535 – 542. DOI: j.colsurfb.2017.09.060

Fornaguera C., García-Celma M.J., PERSONALIZED NANOMEDICINE: A REVOLUTION AT THE NANOSCALE. Journal of Personalized Medicine; Special Issue: Personalized Nanomedicine 7(4),(2017) pii: E12. DOI: 10.3390/jpm7040012

Fornaguera C., Lázaro M.A., Brugada P., Porcar I., Morera I., Guerra-Rebollo M., Garrido C., Rubió N., Blanco J., Cascante A., Borrós S., APPLICATION OF AN ASSAY CASCADE METHODOLOGY FOR A DEEP PRECLINICAL CHARACTERIZATION OF POLYMERIC NANOPARTICLES AS A TREATMENT FOR GLIOMAS. Drug Delivery 25(1) (2018) 472 – 483. DOI: 10.1080/10717544.2018.1436099

Fornaguera C., Guerra-Rebollo M., Lázaro M.A., Castells-Sala C., Ramos V., Cascante A., Rubió N., Blanco J., Borrós S., mRNA delivery system for targeting antigen-presenting cells  in vivo. Advanced Healthcare Materials 7(17) (2018) 1800335. DOI: 10.1002/adhm.201800335

Fornaguera C.,Solans C., ANALYTICAL METHODS TO CHARACTERIZE AND PURIFY POLYMERIC NANOPARTICLES. International Journal of Polymer Science,Volume 2018, Article ID 6387826, 10 pages (2018). DOI: 10.1155/2018/6387826.

Fornaguera C.,Solans C., CHARACTERIZATION OF POLYMERIC NANOPARTICLE DISPERSIONS: SIZE, SURFACE CHARGE AND STABILITY. Pharmaceutical Nanotechnology

(2018) 6(1). DOI: 10.2174/2211738506666180706121515.

Feiner-Gracia N., Dols-Pérez A., Royo M., Solans C., García-Celma M.J., Fornaguera C., CELL PENETRATING PEPTIDE GRAFTING OF PLGA NANOPARTICLES TO ENHANCE CELL UPTAKE. European Polymer Journal, 2018. DOI: 10.1016/j.eurpolymj.2018.09.026.

Fornaguera C.,CHARACTERIZATION OF THE INTERACTION BETWEEN NANOMEDICINES AND BIOLOGICAL COMPONENTS: IN VITRO EVALUATION. Edited by: Raj Bawa, János Szebeni, Thomas J. Webster, and Gerald F. Audette (Editors): Immune Aspects of Biopharmaceuticals and Nanomedicines, Pan Stanford Publishing, Singapore (2018). [ISBN 978-981-4774-52-9 (Hardbound), 978-0-203-73153-6 (eBook)], In press. Book chapter.

 

Grup d’Enginyeria de Materials