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Home ❯ Research Groups ❯ AppLightChem – Applied Photobiological Chemistry

AppLightChem – Applied Photobiological Chemistry

2021 SGR 01023

Coordinator

Santiago Nonell Marrugat, PhD

AppLightChem is a research group that specializes in the biomedical applications and chemical aspects of photonics. It focuses its research and transfer activities on solar photoprotection, cancer photochemotherapy, photoantimicrobial therapies and fluorescence imaging. AppLightChem develops advanced chemical technologies for photoprotection, diagnosis and treatment of diseases with light-activated drugs.

The group is an international leader in its field and has a significant number of international and corporate collaborations. It has been recognised by AGAUR as a Consolidated Research Group since 2021.

In this environment, AppLightChem carries out its RD and technology transfer activities on the following areas:

  • Biological photochemistry
  • Photofunctional molecules and nanomaterials
  • New strategies in antimicrobial photodynamic therapy: genetically encoded photosensitisers, peptide-photosensitiser conjugates and multi-cationic photosensitisers
  • Photodynamic therapy and theragnostic applications of light
  • New strategies in singlet oxygen detection using fluorescence probes
  • Photoprotective solar filters
  • Photoelectrochemistry of nanostructured semiconductive electrodes

Members

M. Josefa Blanco Roca, PhD

Department of Analytical and Applied Chemistry
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Maria Immaculada Passaret i Valls

IQS Tech Transfer

Santiago Nonell Marrugat, PhD

Department of Analytical and Applied Chemistry

Mireia Jordà Redondo

Department of Analytical and Applied Chemistry

Oscar Gulías Borau, PhD

Department of Bioengineering

Roger Bresolí Obach, PhD

Department of Analytical and Applied Chemistry
Avatar

Sergio Adán Bermudéz, PhD

Department of Analytical and Applied Chemistry

M. Josefa Blanco Roca, PhD

Department of Analytical and Applied Chemistry

Avatar

Maria Immaculada Passaret i Valls

IQS Tech Transfer

Santiago Nonell Marrugat, PhD

Department of Analytical and Applied Chemistry

Mireia Jordà Redondo

Department of Analytical and Applied Chemistry

Oscar Gulías Borau, PhD

Department of Bioengineering

Roger Bresolí Obach, PhD

Department of Analytical and Applied Chemistry

Avatar

Sergio Adán Bermudéz, PhD

Department of Analytical and Applied Chemistry

External colaborators

Giovanni Romano, PhD

Università degli Studi di Firenze

Nelly Henry, PhD

Sorbonne Université, Campus Pierre et Marie Curie

Emilio Palomares, PhD

Institut Català d’Investigació Química (ICIQ)

Elena Reddi, PhD

Università di Padova

Karas Kadioglu, PhD

Liverpool University

Glyn Taylor, PhD

Cardiff Scintigraphics Limited (i2c)

Giovanni Romano, PhD

Università degli Studi di Firenze

Nelly Henry, PhD

Sorbonne Université, Campus Pierre et Marie Curie

Emilio Palomares, PhD

Institut Català d’Investigació Química (ICIQ)

Elena Reddi, PhD

Università di Padova

Karas Kadioglu, PhD

Liverpool University

Glyn Taylor, PhD

Cardiff Scintigraphics Limited (i2c)

Research projects

Dispositivo fotónico en cirugía: Eliminación de células cancerosas residuales

Dispositivo fotónico para visualización de tumores y eliminación de células cancerosas residuales
AppLightChem – Applied Photobiological Chemistry

LIGHT4LUNGS (Fotones y radicales de O2 para combatir infecciones resistentes a antibioticos)

Desarrollo de un aerosol innovador que alimenta con fotones las vías respiratorias generando radicales de oxígeno para combatir infecciones de las vías respiratorias resistentes al uso de antibióticos.
AppLightChem – Applied Photobiological Chemistry

Anticuerpos monoclonales modificados con agentes foto- y quimioterapéuticos

Anticuerpos monoclonales modificados con agentes foto y quimioterapéuticos: conjugados ternarios
AppLightChem – Applied Photobiological Chemistry

PhotoSMS (Terapia fotodinámica en cancer)

Nanosistemas multifuncionales autoensamblados para aplicaciones fototeranósticas.
AppLightChem – Applied Photobiological Chemistry

Theranostic photosensitizers (Phosphorescence-guided surgery combined with photodynamic therapy)

Photodynamic therapy uses harmless light in live cells and animal to activate non- toxic photosensitive chemicals photosensitizers to generate cytotoxic species for malignant cell eradication (cancer cells, bacterial infections).
AppLightChem – Applied Photobiological Chemistry

Chemphot (chemistry of photons: from photobiology to optical matter)

Innovative treatment of infections and cancer using real-time monitoring of Reactive Oxygen Species (ROS) using self-reporting non-toxic photosensitizers
AppLightChem – Applied Photobiological Chemistry

INVESTIGO AppLightChem 100045ID15

Nanosistemes multifuncionals autoassemblats per a aplicacions fototeranostiques
AppLightChem – Applied Photobiological Chemistry

SWIR (Automatic processing of shortwave infrared images: first steps towards cancer theragnosis using photobiological chemistry)

This project is based on the application of shortwave infrared (SWIR) for cancer therapy
AppLightChem – Applied Photobiological Chemistry

Llampec (Espectrofotòmetre làser per a l’estudi de processos fotoquímics ultraràpids)

Desenvolupament d'un espectrofotòmetre làser de baix cost per a l'estudi de processos fotoquímics ultraràpids
AppLightChem – Applied Photobiological Chemistry

Facilities

Photochemistry Laboratory

It focuses its research activity on photochemistry and the interrelationships of light with molecules, materials and biological systems. It carries out RDI activities and knowledge and technology transfer in solar photoprotection, cancer photochemotherapy, photoantimicrobial therapies and fluorescence imaging.

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