Dr. Francesc Canals Suris


Research Scientist
Head of the Proteomics Laboratory, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron University Hospital. Barcelona
email: 
francesc.canals@iqs.edu; fcanals@ir.vhebron.net

Graduation in Chemistry (1982, IQS, Barcelona) and Biochemistry (1987, Universitat Autònoma de Barcelona).
PhD in Organic Chemistry (1989, IQS, Barcelona, research work carried out at IQS and at Max-Plank-Institüt für Strahlenchemie, Mulheim, Germany).
Post-doctoral fellow in Biochemistry (1989-1991, University of California, San Diego, USA).
Research Scientist (1991-1995, Institut de Biotecnologia i Biomedicina Universitat Autònoma de Barcelona).
Head of Proteomics (1995-2003 Proteomics and Bioinformatics Facility, Universitat Autònoma de Barcelona).
Head of Proteomics Laboratory (2003-, Vall d’Hebron Institute of Oncology, Barcelona).
 

SUBJECTS

Applications of Genomics, Proteomics and HTS (3 ECTS).
 
 

RESEARCH AREA

Proteomics applied to biomedical research, particularly in oncology. Mass spectrometry and protein array based proteomic analysis. Current research is focused on the application of proteomic techniques to the identification and characterization of substrates of metalloproteases of the ADAM and ADAMTS families, to elucidate their role in tumor growth and metastasis. 
 
 

RECENT PUBLICATIONS

E Martino-Echarri; R Fernández-Rodríguez; JJ Bech-Serra; Mdel C Plaza-Calonge; N Vidal; C Casal; N Colomé; J. Seoane; F Canals; JC Rodríguez-Manzaneque. (2014) Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1. Oncotarget.  Jun 30; 5(12), 4295 – 304
 
Segura V, Medina-Aunon JA, Guruceaga E, Gharbi SI, González-Tejedo C, Sánchez del Pino MM, Canals F, Fuentes M, Casal JI, Martínez-Bartolomé S, Elortza F, Mato JM, Arizmendi JM, Abian J, Oliveira E, Gil C, Vivanco F, Blanco F, Albar JP, Corrales FJ; (2013) Spanish human proteome project: dissection of chromosome 16. J Proteome Res. 2013 Jan 4;12(1):112-22
 
Collado JA, Alvarez I, Ciudad MT, Espinosa G, Canals F, Pujol-Borrell R, Carrascal M, Abian J, Jaraquemada D. (2013) Composition of the HLA-DR-associated human thymus peptidome.
Eur J Immunol. Sep; 43(9):2273-82.