• Dra. Mercedes Balcells Camps

Dra. Mercedes Balcells Camps
Grupo de Ingeniería Vascular y Biomedicina Aplicada
Departamento de Bioingeniería
IQS
Universitat Ramon Llull
Via Augusta 390, E-08017 Barcelona, Spain
Tel. +34 93 267 20 00
Fax +34 93 205 62 66

Harvard-MIT Biomedical Engineering Center
Massachusetts Institut of Technology (MIT)
77 Massachusetts Avenue, Building E25, room 438
Cambridge, MA 02139
Tel. ++ 1 617 324 0054
Fax. ++ 1 617 253 2514
merche@mit.edu

email: 
merce.balcells@iqs.es

Doctora en Ciencias, Química Macromolecular (1999, Rheinisch-Westfälische Technische Hochschule Aachen, RWTH Aachen). Licenciada en Ciencias Químicas (1996, URL). Ingeniera Química (1995, IQS).


Profesora titular, IQS School of Engineering, Departamento de Bioingeniería (2007-)
Principal Research Scientist, MIT Institute for Medical Engineering and Science (2016 – )
Co-fundadora y directora del programa MIT-Spain Program, MIT International Science and Technology Initiatives (2006 –)
Directora del programa IDEA2, MIT LinQ Innovation Initiative (2016 –)

 

Asignaturas

Diseño i aplicación de biomateriales. Cultivos celulares e ingeniería de tejidos. 

 

Líneas de Investigación

  • Impacto del entorno hemodinámico en la funcionalidad de las células  vasculares.
  • Desarrollo  de modelos in vitro para el diagnóstico temprano de la enfermedad cardiovascular, cerebrovascular y mental.
  • Suministro controlado de fármacos mediante dispositivos médicos. 

 

Publicaciones relevantes

“Assessment of the Angiogenic Potential of 2-Deoxy-D-Ribose Using a Novel in vitro 3D Dynamic Model in Comparison With Established in vitro Assays”. Dikici S, Aldemir Dikici B, Bhaloo SI, Balcells M, Edelman ER, MacNeil S, Reilly GC, Sherborne C, Claeyssens F. Front Bioeng Biotechnol. 2020 Jan 17;7:451. doi: 10.3389/fbioe.2019.00451.

“Design, construction and validation of an Alzheimer’s Disease model in human astrocytes for in vitro study of blood-brain barrier degeneration”. Molins B, Mora A, Romero-Vázquez S, Pascual-Méndez A, Rovira S, Figueras-Roca M, Balcells M, Adán A, Martorell J. Exp Eye Res. 2019 Aug 5;187:107751.

"Subendothelial matrix components influence endothelial cell apoptosis in vitro". Saemisch M, Balcells M,  Riesinger L, Nickmann M, Bhaloo S, Edelman ER, Methe M. Am J Physiol Cell Physiol. 2019 Feb 1;316(2):C210-C222.

“Cerebral Small Vessel Disease: A Review Focusing on Pathophysiology, Biomarkers, and Machine Learning Strategies”. Cuadrado-Godia E, Dwivedi P, Sharma S, Ois Santiago A, Roquer Gonzalez J, Balcells M, Laird J, Turk M, S. Suri H, Nicolaides A, Saba L, N. Khanna N, S. Suri J. J Stroke. 2018 Sep; 20(3): 302–320.

“Chondroitin sulphate attenuates atherosclerosis in ApoE Knockout mice involving cellular regulation of the inflammatory response”. Melgar-Lesmes P, Sánchez-Herrero A, Lozano-Juan F, de la Torre Hernández JM, Montell E, Jiménez W, Edelman ER,  and Balcells. Tromb Haemost.  2018 Jul;118(7):1329-1339.

“Optimizing Glutaraldehyde-Fixed Tissue Heart Valves with Chondroitin Sulfate Hydrogel for Endothelialization and Shielding against Deterioration“. Lopez-Moya M, Melgar-Lesmes P, Kolandaivelu K, de la Torre Hernańdez JM, Edelman ER, and M. Balcells. Biomacromolecules 2018 Apr 9;19(4):1234-1244.

“Arterial pulse attenuation prediction using the decaying rate of a pressure wave in a viscoelastic material model.” Menacho J, Rotllant L, Molins JJ, Reyes G, García-Granada AA, Balcells M, Martorell J. Biomech Model Mechanobiol. 2018 Apr;17(2):589-603.

“Targeting STUB1–tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk”. Shashar M, E. Belghasem M, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, B. Kolachalama V, Balcells M, Odagi M, Nagasawa K, M. Henderson J, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, H. Sherr D, R. Edelman E, Ravid K, C. Chitalia V. Sci Transl Med.
2017 Nov 22; 9(417).

“Randomized comparison of ridaforolimus-eluting and zotarolimus-eluting coronary stents in patients with coronary artery disease: primary results from the BIONICS trail.” Kandzari, DE, Smits, PC, Love, MP, Ben-Yehuda, O, Banai S, Robinson, SD, Jonas, M, Kornowski, R, Bagur, R, Iniguez, A, Danenberg, HD, Feldman, RL, Jauhar, R, Chandna H, Parikh, MA, Perlman, GY, Balcells, M, Markham, PM, Ozan, MO, Genereux, P, Edelman, E, Leon, MB, Stone, GW. Circulation. 2017 Aug 9. pii: CIRCULATIONAHA.117.028885. doi: 10.1161/CIRCULATIONAHA.117.028885. 

 

Grupos de investigación

Grupo de Ingeniería Vascular y Biomedicina Aplicada (GEVAB)
Edelman Lab, Harvard-MIT Biomedical Engineering Center